Author

B. Croker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Carlin· 1 shared A. Clark· 1 shared A. De Angelis· 1 shared A. L. Oom· 1 shared B. Deskin· 1 shared C. Fraser· 1 shared C. Sodhi· 1 shared C. Stoneham· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Carlin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

S. H. Park, H. Siddiqi, D. Castro, A. De Angelis, A. L. Oom, C. Stoneham, M. Lewinski, A. Clark, B. Croker, A. Carlin, J. Guatelli, S. J. Opella

This study investigates the structure of SARS-CoV-2 E protein and its interactions with amilorides, finding that binding affinity correlates with antiviral activity and that residue Asn15 is critical for maintaining the binding site conformation.

bioRxiv · Apr 6, 2021Biochemistry

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity

Z. Inde, C. Yapp, G. N. Joshi, J. Spetz, C. Fraser, B. Deskin, E. Ghelfi, C. Sodhi, D. Hackam, L. Kobzik, B. Croker, D. Brownfield, H. Jia, K. A. Sarosiek

The paper examines age-related changes in ACE2 expression and apoptosis regulation in lung tissue, linking these to differences in COVID-19 severity across age groups.

bioRxiv · Sep 13, 2020Cell Biology