Author

A. Carlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Clark· 2 shared L. Wang· 2 shared A. De Angelis· 1 shared A. E. Clark· 1 shared A. L. Oom· 1 shared B. Croker· 1 shared B. D. Gastfriend· 1 shared C. Benner· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

A. Clark

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Interferon-Inducible Guanylate-Binding Protein 5 Inhibits Replication of Multiple Viruses by Binding to the Oligosaccharyltransferase Complex and Inhibiting Glycoprotein Maturation

S. Wang, W. Li, L. Wang, S. K. Tiwari, W. Bray, L. Wu, N. Li, H. Hui, A. Clark, Q. Zhang, L. Zhang, A. Carlin, T. M. Rana

This paper identifies GBP5 as an ISG that inhibits viral replication by blocking N-glycosylation of viral proteins, including SARS-CoV-2 spike, through interaction with the OST complex.

bioRxiv · May 1, 2024Microbiology

Transcriptional regulatory features associated with Coccidioides immitis phase transition

S. H. Duttke, S. Beyhan, R. Singh, S. E. Neal, S. Viriyakosol, J. Fierer, T. N. Kirkland, J. E. Stajich, C. Benner, A. Carlin

This study uses csRNA-seq to identify transcriptional changes and regulatory elements during phase transition in Coccidioides immitis, revealing a WOPR homologue involved in pathogenicity.

bioRxiv · Jul 22, 2021 · PreprintImmunology

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

S. H. Park, H. Siddiqi, D. Castro, A. De Angelis, A. L. Oom, C. Stoneham, M. Lewinski, A. Clark, B. Croker, A. Carlin, J. Guatelli, S. J. Opella

This study investigates the structure of SARS-CoV-2 E protein and its interactions with amilorides, finding that binding affinity correlates with antiviral activity and that residue Asn15 is critical for maintaining the binding site conformation.

bioRxiv · Apr 6, 2021Biochemistry

A Human 3D neural assembloid model for SARS-CoV-2 infection

J. G. Gleeson, L. Wang, D. Sievert, A. E. Clark, H. Federman, B. D. Gastfriend, E. Shusta, S. Palecek, A. Carlin, A. E. Clark

This study demonstrates that pericyte-like cells in cortical organoids can support SARS-CoV-2 infection and replication, serving as a new model for neural infection.

bioRxiv · Feb 9, 2021Microbiology