Author

A. L. Oom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

J. Guatelli· 3 shared C. Stoneham· 2 shared M. K. Lewinski· 2 shared A. A. Aksenov· 1 shared A. Bouslimani· 1 shared A. Campeau· 1 shared A. Carlin· 1 shared A. Clark· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

J. Guatelli

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

S. H. Park, H. Siddiqi, D. Castro, A. De Angelis, A. L. Oom, C. Stoneham, M. Lewinski, A. Clark, B. Croker, A. Carlin, J. Guatelli, S. J. Opella

This study investigates the structure of SARS-CoV-2 E protein and its interactions with amilorides, finding that binding affinity correlates with antiviral activity and that residue Asn15 is critical for maintaining the binding site conformation.

bioRxiv · Apr 6, 2021Biochemistry

Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression

A. L. Oom, C. A. Stoneham, M. K. Lewinski, A. Richards, J. Wozniak, K. Shams-Ud-Doha, D. Gonzalez, N. J. Krogan, J. Guatelli

The paper compares machine learning methods for spatial proteome classification in HIV-expressing T cells and identifies Nef-dependent interactors.

bioRxiv · Mar 17, 2021Cell Biology

Functional Landscape of SARS-CoV-2 Cellular Restriction

L. Martin-Sancho, M. K. Lewinski, L. Pache, C. Stoneham, X. YIN, D. Pratt, C. Churas, S. B. Rosenthal, S. Liu, P. D. De Jesus, A. M. O'Neill, A. P. Gounder, C. Nguyen, Y. Pu, A. L. Oom, , S. Chanda

This study identifies key interferon stimulated genes (ISGs) that restrict SARS-CoV-2 infection by inhibiting viral entry, RNA synthesis, and release.

bioRxiv · Sep 29, 2020Microbiology

Untargeted Mass Spectrometry-Based Metabolomics Tracks Molecular Changes in Raw and Processed Foods and Beverages

J. M. Gauglitz, C. M. Aceves, A. A. Aksenov, G. Aleti, J. Almaliti, A. Bouslimani, E. A. Brown, A. Campeau, A. M. Caraballo-Rodriguez, R. Chaar, R. R. da Silva, A. M. Demko, F. Di Ottavio, E. Elijah, M. Ernst, , W

This paper uses untargeted mass spectrometry to analyze chemical changes in foods during preparation and storage, finding that some processes alter molecular composition while others primarily involve extraction.

bioRxiv · Jun 15, 2018 · PreprintBiochemistry