The AMIGO1 adhesion protein activates Kv2.1 voltage sensors
R. J. Sepela, R. G. Stewart, L. Valencia, P. Thapa, Z. Wang, B. E. Cohen, J. T. Sack
This study identifies how AMIGO1 modulates Kv2.1 voltage sensor movements and conductance activation by destabilizing the earliest resting state.
bioRxiv · Jun 20, 2021Biophysics