The lysosomal TRPML1 channel promotes breast cancer survival by supporting mitochondrial function and cellular metabolism
S. Almasi, B. E. Kennedy, R. E. Yoast, S. M. Emrich, M. Trebak, Y. El Hiani
This study shows TRPML1 promotes TNBC survival by supporting mitochondrial function and metabolism, and its inhibition enhances chemotherapy effectiveness.
bioRxiv · Sep 4, 2020 · PreprintCancer Biology