Author

B. Guertl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K. Klavins· 3 shared J. Menche· 2 shared K. L. Bennett· 2 shared P. Majek· 2 shared A. Bergthaler· 1 shared A. Bhattacharya· 1 shared A. C. Mueller· 1 shared A. Lercher· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

K. Klavins

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

M. Rebsamen, E. Girardi, V. Sedlyarov, K. Papakostas, J. Konecka, M. Vollert, S. Scorzoni, B. Guertl, K. Klavins, T. Wiedmer, G. Superti-Furga

This study uses gain-of-function genetic screens in human cells to identify SLC transporters that overcome nutrient limitations by enhancing uptake of essential amino acids.

bioRxiv · Apr 3, 2022Cell Biology

Ifnar1 signaling breaks the hepatic urea cycle to regulate adaptive immunity

A. Lercher, A. Bhattacharya, A. M. Popa, M. Caldera, M. F. Schlapansky, H. Baazim, P. Majek, J. S. Brunner, L. J. Kosack, D. Vitko, T. Pinter, B. Guertl, D. Reil, U. Kalinke, K. L. Bennett, , A. Bergthaler

This study shows that IFN-I signaling in the liver disrupts the urea cycle, reducing arginine and increasing ornithine, which suppresses CD8 T cell responses and improves liver pathology during viral infection.

bioRxiv · Sep 10, 2019 · PreprintImmunology

MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation

S. Sdelci, A. Rendeiro, P. Rathert, G. Hofstaetter, A. Ringler, H. P. Moll, W. You, K. Klavins, B. Guertl, M. Farlik, S. Schick, F. Klepsch, M. Oldach, P. Buphamalai, F. Schischlik, , S. Kubicek

This study identifies MTHFD1 as a genetic and physical interactor of BRD4, linking folate metabolism to transcriptional regulation and showing synergistic effects on cancer cell viability.

bioRxiv · Oct 10, 2018Cancer Biology