Platelets are dispensable for the ability of CD8+ T cells to accumulate, patrol, kill and reside in the liver
J. H. O'Connor, H. A. McNamara, Y. Cai, L. A. Coupland, E. E. Gardiner, C. R. Parish, B. J. McMorran, V. V. Ganusov, I. A. Cockburn
This study shows that platelets are not essential for CD8+ T cell accumulation, patrolling, killing, and residency in the liver, while ASGP-expressing cells are retained in the liver but lost from the spleen.
bioRxiv · Nov 9, 2021 · PreprintImmunology