Author

E. E. Gardiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Organism:mouse· 2

Frequent Co-Authors

T. Xu· 3 shared Y. J. Lim· 3 shared C. R. Parish· 2 shared H. Lin· 2 shared S. M. Hicks· 2 shared W. M. Lee· 2 shared Y. Zheng· 2 shared A. Aggarwal· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

T. Xu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Glycoprotein VI is Critical for the Detection and Progression of Abdominal Aortic Aneurysms

T. W. Benson, M. M. Pike, A. Spuzzillo, S. M. Hicks, M. Pham, D. S. Mix, S. I. Brunner, C. A. Wadding-Lee, K. A. Conrad, H. M. Russell, C. Jennings, T. M. Coughlin, A. Aggarwal, S. Lyden, K. Mani, , A. P. Owens

This study identifies glycoprotein VI as a critical factor in AAA detection and progression, showing its predictive value in humans and therapeutic potential in mice.

bioRxiv · Jul 2, 2023 · PreprintPathology

Combined Scattering, Interferometric and Fluorescence Oblique Illumination for Live Cell Nanoscale Imaging

Y. Zheng, Y. J. Lim, H. Lin, T. Xu, C. Longbottom, V. Delghingaro-Augusto, Y. L. Thong, C. R. Parish, E. E. Gardiner, W. M. Lee

This paper develops a combined imaging system for live cell nanoscale imaging, enabling the simultaneous quantification of molecular targets, 3D cell morphodynamics, and intracellular organelle tracking.

bioRxiv · Jul 22, 2022Biophysics

Patterning High to Low Heterogenous Fluid Shear Stress Landscapes with Multiphoton Inner Laser Lithography (MILL) for Live Cell Adhesion and Translocation

Y. J. Lim, J. Zhang, H. Lin, T. Xu, Y. Li, Z. Zhang, S. M. Hicks, I. Chudinov, D. Y. Nechipurenko, E. E. Gardiner, w. m. Lee

The paper develops MILL, a technique to rapidly create 3D micro-patterned flow channels that mimic in vivo fluid shear stress environments, enabling real-time study of cell adhesion and translocation.

bioRxiv · Jun 17, 2022 · PreprintBioengineering

Platelets are dispensable for the ability of CD8+ T cells to accumulate, patrol, kill and reside in the liver

J. H. O'Connor, H. A. McNamara, Y. Cai, L. A. Coupland, E. E. Gardiner, C. R. Parish, B. J. McMorran, V. V. Ganusov, I. A. Cockburn

This study shows that platelets are not essential for CD8+ T cell accumulation, patrolling, killing, and residency in the liver, while ASGP-expressing cells are retained in the liver but lost from the spleen.

bioRxiv · Nov 9, 2021 · PreprintImmunology

COSI for label-free multiparameter quantitative imaging of intra-thrombus stability in vitro.

Y. Zheng, S. Montague, Y. J. Lim, T. Xu, T. Xu, E. E. Gardiner, S. Lee

This paper introduces COSI, a label-free imaging method to quantify intra-thrombus mass and adhesive platelet dynamics under fluid shear stress with high precision.

bioRxiv · Aug 17, 2020 · PreprintBioengineering

Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets.

C. Pallini, J. A. Pike, C. O'Shea, R. K. Andrews, E. E. Gardiner, S. P. Watson, N. S. Poulter

This study shows immobilized collagen prevents GPVI shedding and sustains its clustering and signaling in platelets for at least 3 hours.

bioRxiv · Jul 7, 2020 · PreprintCell Biology