Author

B. J. Tuck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

W. A. McEwan· 2 shared A. K. Davies· 1 shared C. Knox· 1 shared E. L. Wilson· 1 shared E. Metzakopian· 1 shared G. H. H. Borner· 1 shared J. P. Schessner· 1 shared L. C. James· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

W. A. McEwan

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Author profile →

2 papers

Recent·Most cited

Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells

P. Rodriguez-Silvestre, M. Laub, A. K. Davies, J. P. Schessner, P. A. Krawczyk, B. J. Tuck, W. A. McEwan, G. H. H. Borner, P. Kozik

The paper identifies perforin-2 as a pore-forming protein essential for endocytic escape in cross-presenting dendritic cells, enabling antigen processing for MHC class I presentation.

bioRxiv · Jan 31, 2023Cell Biology

Tau assemblies enter the cytosol in a cholesterol sensitive process essential to seeded aggregation

B. J. Tuck, L. V. C. Miller, E. L. Wilson, T. Katsinelos, S. Cheng, M. J. Vaysburd, C. Knox, L. Tredgett, E. Metzakopian, L. C. James, W. A. McEwan

The paper investigates how tau assemblies enter the cytosol, finding that cholesterol levels and specific cellular machinery are critical for this process, which is essential for seeded aggregation.

bioRxiv · Jun 21, 2021Cell Biology