Author

A. K. Davies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

G. H. H. Borner· 4 shared J. P. Schessner· 2 shared M. S. Robinson· 2 shared A. Sanger· 1 shared B. J. Tuck· 1 shared D. C. Gershlick· 1 shared D. Ebrahimi-Fakhari· 1 shared D. N. Itzhak· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersCell Biology

G. H. H. Borner

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5 papers

Recent·Most cited

The role of the AP-1 adaptor complex in outgoing and incoming membrane traffic

M. S. Robinson, R. Antrobus, A. Sanger, A. K. Davies, D. C. Gershlick

The paper investigates AP-1 function in membrane traffic, showing it retrieves proteins from post-Golgi compartments back to the TGN, similar to COPI's role in the early secretory pathway.

bioRxiv · Nov 2, 2023Cell Biology

Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells

P. Rodriguez-Silvestre, M. Laub, A. K. Davies, J. P. Schessner, P. A. Krawczyk, B. J. Tuck, W. A. McEwan, G. H. H. Borner, P. Kozik

The paper identifies perforin-2 as a pore-forming protein essential for endocytic escape in cross-presenting dendritic cells, enabling antigen processing for MHC class I presentation.

bioRxiv · Jan 31, 2023Cell Biology

Deep and fast label-free Dynamic Organellar Mapping

J. P. Schessner, V. Albrecht, A. K. Davies, P. Sinitcyn, G. H. H. Borner

This paper introduces DIA-DOMs, a method enhancing subcellular protein localization profiling using DIA-MS, and presents DOM-QC for analysis, showing improved depth, precision, and throughput in HeLa cells.

bioRxiv · Nov 9, 2021Biochemistry

AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB

A. K. Davies, M. Ziegler, H. Jumo, W. Afshar Saber, D. Ebrahimi-Fakhari, G. H. H. Borner

The paper identifies DAGLB as an AP-4 cargo, showing its axonal targeting and role in 2-AG signaling, which may explain axon growth defects in AP-4 deficiency.

bioRxiv · Oct 25, 2020 · PreprintCell Biology

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A

A. K. Davies, D. N. Itzhak, J. R. Edgar, T. L. Archuleta, J. Hirst, L. P. Jackson, M. S. Robinson, G. H. H. Borner

The paper identifies AP-4's role in ATG9A trafficking via RUSC2-mediated vesicle transport, linking AP-4 deficiency to autophagy dysregulation in multiple cell types.

bioRxiv · Jun 11, 2018Cell Biology