Cell BiologybioRxiv
Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells
P. Rodriguez-Silvestre, M. Laub, A. K. Davies…·P. Kozik
The paper identifies perforin-2 as a pore-forming protein essential for endocytic escape in cross-presenting dendritic cells, enabling antigen processing for MHC class I presentation.
DOI 10.1126/science.adg8802