Author

B. L. Hodges

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:protein structure· 1

Frequent Co-Authors

D. Armstrong· 2 shared G. L. Austin· 2 shared J. R. Pauly· 2 shared A. DePaoli-Roach· 1 shared A. Uittenbogaard· 1 shared C. W. Vander Kooi· 1 shared D. M. Segvich· 1 shared J. E. Klier· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

D. Armstrong

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2 papers

Recent·Most cited

Targeting pathogenic Lafora bodies in Lafora disease using an antibody-enzyme fusion

M. K. Brewer, A. Uittenbogaard, G. L. Austin, J. J. McCarthy, D. M. Segvich, A. DePaoli-Roach, P. J. Roach, B. L. Hodges, J. Zeller, J. R. Pauly, T. McKnight, D. Armstrong, M. Gentry

This paper develops an antibody-enzyme fusion that degrades Lafora bodies in a mouse model of Lafora disease, reducing LB load and showing therapeutic potential.

bioRxiv · Jun 21, 2019Biochemistry

Central Nervous System Delivery and Biodistribution Analysis of an Antibody-Enzyme Fusion for the Treatment of Lafora Disease

G. L. Austin, Z. R. Simmons, J. E. Klier, B. L. Hodges, R. Shaffer, T. R. McKnight, J. R. Pauly, D. Armstrong, C. W. Vander Kooi, M. S. Gentry

This study evaluates the cerebral delivery and biodistribution of VAL-0417, an antibody-enzyme fusion for Lafora disease, showing intracerebroventricular administration is most effective.

bioRxiv · Jun 14, 2019Bioengineering