R. Gross

Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection

This study identifies glycomic alterations in HIV-positive individuals that correlate with accelerated aging and comorbidities, suggesting potential biomarkers for early detection.

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.

Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

This study identifies ultrapotent bispecific antibodies that neutralize emerging SARS-CoV-2 variants by targeting multiple spike protein regions, showing efficacy in vitro and in a hamster model.

Acute myeloid leukemia cells are targeted by the naturally occurring CXCR4 antagonist EPI-X4

The paper was withdrawn due to unresolved data contribution and authorship issues, and the authors request it not be cited as a reference.

Scalable, Micro-Neutralization Assay for Qualitative Assessment of SARS-CoV-2 (COVID 19) Virus-Neutralizing Antibodies in Human Clinical Samples

The paper describes a modified fluorescence reduction neutralization assay for quantitatively assessing SARS-CoV-2 neutralizing antibodies in clinical samples, demonstrating its efficiency and accuracy.

Negatively charged peptide nanofibrils from immunoglobulin light chain sequester viral particles but lack cell-binding and viral transduction-enhancing properties

The paper shows that negatively charged peptide nanofibrils from immunoglobulin light chain bind viral particles similarly to positively charged ones but do not enhance retroviral infection.

Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro

This study evaluates the antiviral effects of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro, finding that chokeberry juice inactivates SARS-CoV-2 and influenza virus, while other products show limited efficacy.

Natural Cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling

The paper identifies a Cystatin C fragment that inhibits GPR15-mediated HIV and SIV infection without affecting GPR15L signaling.

An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection

This paper introduces an enzyme-based immunodetection assay to quantify SARS-CoV-2 infection by measuring viral spike protein expression in cell cultures.

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

This study shows that IFITM proteins are required for SARS-CoV-2 infection and can be targeted to inhibit viral entry and replication.

Alpha-1 antitrypsin inhibits SARS-CoV-2 infection

The paper identifies 1-antitrypsin as a specific inhibitor of SARS-CoV-2, showing it blocks viral infection of human airway epithelium at physiological concentrations.

Holder Pasteurization Inactivates SARS-CoV-2 in Human Breast Milk

This study shows that Holder pasteurization inactivates SARS-CoV-2 in human breast milk, offering a safe method for infected mothers to breastfeed.

Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids

This study uses human intestinal organoids to show that remdesivir inhibits SARS-CoV-2 replication, while famotidine does not.

The Zinc Finger Antiviral Protein restricts SARS-CoV-2

This paper identifies ZAP as an IFN-induced antiviral effector that restricts SARS-CoV-2 by targeting CpG dinucleotides, though SARS-CoV-2 may be adapted to low CpG environments.

Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2

This paper develops SHINE, a diagnostic tool for SARS-CoV-2 detection with 90% sensitivity and 100% specificity, reducing contamination risk and enabling use outside clinical settings.

The strength and form of natural selection on transcript abundance in the wild

The paper estimates natural selection on transcript abundance in wild salmonids infected by a parasite, finding upregulated cell cycle genes and disruptive selection linked to survival.

Formicine ants swallow their highly acidic poison for gut microbial selection and control

The paper shows formicine ants use their acidic poison to control microbial communities in their gut, inhibiting pathogens while promoting beneficial bacteria.