Cell BiologybioRxiv
Multi-color single molecule imaging uncovers extensive heterogeneity in mRNA decoding
S. Boersma, D. Khuperkar, B. M. P. Verhagen…·M. E. Tanenbaum
This study introduces MoonTag, a fluorescence labeling system to visualize single mRNA translation, revealing stochastic start site selection and dynamic regulation in real-time.
DOI 10.1016/j.cell.2019.05.001