B. N. Safa

Aging and intraocular pressure homeostasis in mice

This study examines how aging affects intraocular pressure regulation in mice, finding that outflow facility remains stable despite age-related tissue changes.

A Histomorphometric and Computational Investigation of the Stabilizing Role of Pectinate Ligaments in the Aqueous Outflow Pathway

This study investigates the role of pectinate ligaments in maintaining the biomechanical stability of the aqueous outflow pathway in mice across different ages.

The Effects of Negative Periocular Pressure on Biomechanics of the Optic Nerve Head and Cornea: A Computational Modeling Study

This study uses computational modeling to show that negative periocular pressure reduces optic nerve head strain and increases corneal strain, suggesting potential biomechanical benefits for glaucoma treatment.

In vivo Biomechanical Assessment of Iridial Deformations and Muscle Contractions in Human Eyes

The paper assesses iridial biomechanical deformations and muscle contractions in human eyes using near-infrared movies from the pupillary light reflex to study their role in primary angle-closure glaucoma.

Assessment of the Viscoelastic Mechanical Properties of the Porcine Optic Nerve Head using Micromechanical Testing and Finite Element Modeling

This study measures the viscoelastic properties of porcine optic nerve heads using micromechanical testing and finite element modeling, revealing quadrant-specific mechanical characteristics.

Identifiability of Tissue Material Parameters from Uniaxial Tests using Multi-start Optimization

This paper assesses the identifiability of tissue material parameters from uniaxial tests using synthetic data and multi-start optimization, finding that not all parameters are uniquely identifiable.

Helical Fibrillar Microstructure of Tendon using Serial Block-Face SEM and a Mechanical Model for Interfibrillar Load Transfer

This study uses SBF-SEM and finite element modeling to show that helical fibril arrangements in rat tail tendon enable friction-based load transfer without matrix bonding or fibril fusion.

Evaluating Plastic Deformation and Damage as Potential Mechanisms for Tendon Inelasticity using a Reactive Modeling Framework

This study evaluates plastic deformation and damage as mechanisms for tendon inelasticity using a reactive inelastic model, finding both models fit experimental data but unable to distinguish between the mechanisms.

A Reactive Inelasticity Theoretical Framework for modeling Viscoelasticity, Plastic Deformation, and damage in Soft Tissue

The paper develops a theoretical framework to model inelastic behaviors of soft tissues by linking mechanical responses to biopolymeric structure through reactive bond mechanics.