Author

M. L. De Ieso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

W. D. Stamer· 3 shared M. Kuhn· 2 shared A. J. Feola· 1 shared A. J. Yool· 1 shared A. Singh· 1 shared A. Wilson· 1 shared B. N. Safa· 1 shared C. Bowes Rickman· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersPhysiology

W. D. Stamer

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Author profile →

4 papers

Recent·Most cited

Aging and intraocular pressure homeostasis in mice

G. Li, J. van Batenburg-Sherwood, B. N. Safa, N. S. Fraticelli Guzman, A. Wilson, M. R. Bahrani Fard, K. Choy, M. L. de Ieso, S. Cui, A. J. Feola, T. Weisz, M. Kuhn, C. Bowes Rickman, S. Farsiu, C. R. Ethier, W. D. Stamer

This study examines how aging affects intraocular pressure regulation in mice, finding that outflow facility remains stable despite age-related tissue changes.

bioRxiv · Oct 17, 2023Physiology

Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology

H. Li, M. Kuhn, R. A. Kelly, A. Singh, K. K. Palanivel, I. Salama, M. L. De Ieso, W. D. Stamer, P. S. Ganapathy, S. Herberg

This study investigates how ECM stiffening affects YAP mechanosignaling in SC cells and shows that disrupting YAP signaling improves outflow facility in glaucoma.

bioRxiv · Sep 8, 2023 · PreprintCell Biology

Mechanotransduction and dynamic outflow regulation in trabecular meshwork requires Piezo1 channels

O. Yarishkin, T. T. T. Phuong, J. M. Baumann, M. L. De Ieso, F. Vazquez-Chona, C. N. Rudzitis, C. Sundberg, M. Lakk, W. D. Stamer, D. Krizaj

This study identifies Piezo1 channels as critical for mechanosensitivity in trabecular meshwork cells, showing their role in pressure response, calcium signaling, and outflow regulation.

bioRxiv · Jun 30, 2020 · PreprintPhysiology

Effect of Compound Kushen Injection, a natural compound mixture, and its identified chemical components on migration and invasion of colon, brain and breast cancer cell lines

S. Nourmohammadi, T. N. Aung, J. Cui, J. V. Pei, M. L. De Ieso, Y. Harata-Lee, Z. Qu, D. L. Adelson, A. J. Yool

This study evaluates the effects of Compound Kushen Injection and its components on cancer cell migration and invasion in multiple cell lines, finding reduced motility and invasiveness.

bioRxiv · Dec 19, 2018Cancer Biology