Author

B. R. Haddad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. M. Tiek· 2 shared R. B. Riggins· 2 shared A. Goenka· 1 shared A. M. Alamri· 1 shared B. Erdogdu· 1 shared B. Hu· 1 shared B. J. Davidson· 1 shared B. V. Kallakury· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

D. M. Tiek

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug resistant gliomas

D. M. Tiek, B. Erdogdu, R. Razaghi, L. Jin, N. Sadowski, C. Alamillo-Ferrer, J. R. Hogg, B. R. Haddad, D. H. Drewry, C. I. Wells, J. E. Pickett, X. Song, A. Goenka, B. Hu, S. L. Goldlust, , R. B. Riggins

This study identifies guanine mutations in TMZ-resistant gliomas that disrupt G4 structures and splice sites, creating vulnerabilities targeted by G4 stabilizers and splicing inhibitors.

bioRxiv · Nov 21, 2021Cancer Biology

Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma

D. M. Tiek, J. D. Rone, G. T. Graham, E. L. Pannkuk, B. R. Haddad, R. B. Riggins

This study creates and characterizes two new TMZ-resistant GBM cell lines, revealing distinct phenotypic changes associated with resistance.

bioRxiv · Dec 14, 2017Cancer Biology

Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing

A. M. Alamri, X. Liu, J. K. Blancato, B. R. Haddad, W. Wang, X. Zhong, S. Choudhary, E. Krawczyk, B. V. Kallakury, B. J. Davidson, P. A. Furth

This study establishes a method to expand primary cells from salivary gland neoplasms for genetic and chemosensitivity testing, identifying therapeutic targets and resistance mechanisms.

bioRxiv · Aug 8, 2017Cancer Biology