Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaques
K. J. Hasenkrug, F. Feldmann, L. Myers, M. L. Santiago, K. Guo, B. S. Barrett, K. L. Mickens, A. Carmody, A. Okumura, D. Rao, M. M. Collins, R. J. Messer, J. Lovaglio, C. Shaia, R. Rosenke, , H. Feldmann
This study shows that T cell depletion in rhesus macaques does not cause severe SARS-CoV-2 disease but delays viral clearance, and T cells are not essential for immunological memory or protection against re-infection.
bioRxiv · Apr 2, 2021Immunology