Author

L. Myers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 2 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:host-pathogen & immune response· 6 Organism:human· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 2 Organism:rat· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

A. Trivette· 5 shared E. Binshtein· 5 shared J. E. Crowe· 5 shared R. H. Carnahan· 5 shared E. C. Chen· 4 shared M. S. Diamond· 4 shared N. Suryadevara· 4 shared P. Gilchuk· 4 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

A. Trivette

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Avian influenza viruses in wild birds in Canada following incursion of the highly pathogenic H5N1 virus from Eurasia in 2021/2022

J. A. Giacinti, A. V. Signore, M. E. B. Jones, L. Bourque, S. Lair, C. Jardine, B. Stevens, T. Bollinger, D. Goldsmith, British Columbia Wildlife AIV Surveillance Program (BC WASP), M. Pybus, I. Stasiak, R. Davis, N. Pople, L. Nituch, , Thompson

This study tracks the spread of HPAIV H5N1 in Canadian wild birds after its 2021/2022 incursion, finding widespread infection across species and regions.

bioRxiv · Nov 23, 2023Zoology

A bivalent Adenovirus-Vectored Vaccine induces a measurable humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus

S. van Tol, P. Fletcher, F. Feldmann, R. K. Mukesh, J. R. Port, S. Gallogly, J. E. Schulz, J. F. Roderick, R. Makinson, A. Carmody, L. Myers, J. Lovaglio, B. J. Smith, A. Okumura, C. Shaia, , N. van Doremalen

This study evaluates a bivalent Adenovirus-Vectored Vaccine in cynomolgus macaques against Sudan virus, finding it induces humoral responses but does not confer protection against lethal challenge.

bioRxiv · Oct 20, 2023Microbiology

Rectal and vaginal challenge with mpox virus increases virus dissemination and contact transmission compared to skin challenge in the multimammate rat (Mastomys natalensis)

J. R. Port, J. C. Riopelle, S. G. Smith, L. Myers, M. C. Lewis, S. Gallogly, A. Okumura, J. E. Schukz, R. Rosenke, J. Prado-Smith, A. Carmody, S. Bane, B. J. Smith, G. Saturday, H. Feldmann, , V. J. Munster

This study shows that rectal and vaginal mpox virus inoculation in rats leads to more virus shedding and contact transmission compared to skin inoculation.

bioRxiv · May 7, 2023 · PreprintMicrobiology

Systematic analysis of human antibody response to ebolavirus glycoprotein reveals high prevalence of neutralizing public clonotypes

E. C. Chen, P. Gilchuk, S. J. Zost, P. A. Ilinykh, E. Binshtein, K. Huang, L. Myers, S. Bonissone, S. Day, C. R. Kona, A. Trivette, J. X. Reidy, R. E. Sutton, C. Gainza, S. Monroig, , J. E. Crowe

The paper analyzes the human antibody response to ebolavirus glycoprotein, identifying public clonotypes with neutralizing activity and implications for vaccine design.

bioRxiv · Jan 12, 2022 · PreprintImmunology

An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer

N. Suryadevara, A. Shiakolas, L. VanBlargan, E. Binshtein, R. Chen, J. B. Case, K. Kramer, E. Armstrong, L. Myers, A. Trivette, C. Gainza, R. Nargi, C. Selverian, E. Davidson, B. Doranz, , J. E. Crowe

The paper identifies a rare antibody that targets the SARS-CoV-2 spike trimer interface, disrupting viral entry and providing protection in mice.

bioRxiv · Jan 12, 2022Immunology

Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals

E. C. Chen, P. Gilchuk, S. J. Zost, N. Suryadevara, E. S. Winkler, C. R. Cabel, E. Binshtein, R. E. Sutton, J. L. Rodriguez, S. Day, L. Myers, A. Trivette, J. K. Williams, E. Davidson, S. Li, , J. E. Crowe

The paper identifies public antibody clonotypes in SARS-CoV-2 convalescents and vaccinated individuals, revealing common epitope recognition and potential vaccine efficacy mechanisms.

bioRxiv · May 2, 2021Immunology

Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaques

K. J. Hasenkrug, F. Feldmann, L. Myers, M. L. Santiago, K. Guo, B. S. Barrett, K. L. Mickens, A. Carmody, A. Okumura, D. Rao, M. M. Collins, R. J. Messer, J. Lovaglio, C. Shaia, R. Rosenke, , H. Feldmann

This study shows that T cell depletion in rhesus macaques does not cause severe SARS-CoV-2 disease but delays viral clearance, and T cells are not essential for immunological memory or protection against re-infection.

bioRxiv · Apr 2, 2021Immunology

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

S. J. Zost, P. Gilchuk, J. B. Case, E. Binshtein, R. E. Chen, J. X. Reidy, A. Trivette, R. S. Nargi, R. E. Sutton, N. Suryadevara, L. E. Williamson, E. C. Chen, T. Jones, S. Day, L. Myers, , J. E. Crowe

The paper identifies potent neutralizing antibodies against SARS-CoV-2 that block receptor binding and protect animals, providing insights for vaccine and therapy development.

bioRxiv · May 22, 2020Immunology

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

S. J. Zost, P. Gilchuk, R. Chen, J. B. Case, J. X. Reidy, A. Trivette, R. S. Nargi, R. E. Sutton, N. Suryadevara, E. C. Chen, E. Binshtein, S. Shrihari, M. A. Ostrowski, H. Y. Chu, J. E. Didier, , J. E. Crowe

This study isolates and profiles human monoclonal antibodies against SARS-CoV-2 spike protein, identifying neutralizing antibodies targeting the receptor-binding domain.

bioRxiv · May 12, 2020Immunology