NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity
N. Haider, P. Dutt, B. van de Kooij, M. B. Yaffe, V. Stambolic
This study identifies NEK10 as a kinase that phosphorylates p53 on Y327, modulating its transcriptional activity and affecting cellular proliferation and response to DNA damage.
bioRxiv · Jan 10, 2019Cancer Biology