Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis
X. He, J. Liu, C. Liang, A. B. Shaikh, K. Zheng, L. Dang, B. Guo, D. Li, C. Lu, Q. Guo, D. Fan, Y. Bian, H. Feng, L. Xiao, X. Pan, , A. Lu
This study shows that PLEKHO1 in osteoblasts worsens joint inflammation in RA and promotes bone formation, suggesting it as a therapeutic target.
bioRxiv · Jul 30, 2018Cell Biology