Author

Y. Bian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 2 Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Approach:statistical model· 4 Assay:proteomics· 3 Research Focus:benchmarking· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2

Frequent Co-Authors

J. Liu· 5 shared B. Zhang· 4 shared H. Jiang· 4 shared H. Ma· 4 shared H. Tang· 4 shared H. Yin· 4 shared H. Zong· 4 shared J. Zhu· 4 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersCell Biology

J. Liu

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Structural and functional analysis of the Nipah virus polymerase complex

S. Hu, H. Kim, P. Yang, Z. Yu, B. Ludeke, S. Mobilia, J. Pan, M. Stratton, Y. Bian, R. Fearns, J. Abraham

This study determines the cryo-EM structure of the Nipah virus polymerase complex and identifies key domains critical for replication and transcription.

bioRxiv · May 29, 2024Microbiology

Deciphering the molecular mechanism underlying morphology transition in two-component DNA-protein cophase separation

C. Li, Y. Bian, Y. Tang, L. Meng, P. Yin, Y. Hong, J. Cheng, Y. Li, J. Lin, C. Tang, C. Chen, W. Li, Z. Qi

The paper investigates DNA-protein co-condensates, identifying two morphology transitions and growth dynamics governed by DNA-p53 interaction strength.

bioRxiv · Jan 26, 2024Biophysics

Fusion dynamics and size-dependent droplet microstructure in ssDNA mediated protein phase separation

Y. Bian, W. Li

This study investigates the fusion dynamics and microstructure evolution of biomolecular droplets during ssDNA-protein cocondensation using molecular dynamics simulations.

bioRxiv · Nov 13, 2023 · PreprintBiophysics

Deconvolution Of Hematopoietic Stem/Progenitor Cell Signaling Predicts Inflammatory Niche Remodeling To Be A Determinant Of Tissue Failure And Outcome In Human AML

L. Chen, E. Pronk, C. van Dijk, Y. Bian, J. Feyen, T. van Tienhoven, M. Yildirim, P. Pisterzi, M. de Jong, A. Bastidas, R. Hoogenboezem, C. Wevers, E. Bindels, B. Lowenberg, T. Cupedo, , M. Raaijmakers

The paper uses scRNA-seq to analyze signaling between hematopoietic stem/progenitor cells and their niches in AML, identifying inflammatory niche remodeling as a factor affecting tissue failure and patient outcome.

bioRxiv · May 5, 2023 · PreprintCancer Biology

Knowledge Mapping of Alternative Splicing of Cancer From 2012 to 2021: A Bibliometric Analysis

B. Tian, Y. Bian, D.-J. Bian, Y. Gao, X. Zhang, S.-W. Zhou, Y.-H. Zhang, Y.-N. Pang, Z.-S. Li, L.-W. Wang

This paper conducts a bibliometric analysis of cancer alternative splicing research from 2012 to 2021, identifying trends, key institutions, and research areas.

Frontiers in Oncology · Dec 14, 2022Peer-reviewedCancer Biology

Long-term passaging of replication competent pseudo-typed SARS-CoV-2 reveals the antiviral breadth of monoclonal and bispecific antibody cocktails

J. Zhu, H. Ma, H. Zong, J. Liu, Y. Yue, Y. Ke, Y. Liao, H. Tang, L. Wang, S. Wang, Y. Yuan, M. Wu, Y. Bian, B. Zhang, H. Yin, , Y. Xie

This study evaluates the antiviral breadth of monoclonal and bispecific antibody cocktails against SARS-CoV-2 variants using a replication competent VSV-SARS-CoV-2 model, showing resistance to mutation in two cocktails.

bioRxiv · Oct 5, 2022 · PreprintCell Biology

Efficient Neutralization of SARS-CoV-2 Omicron and Other VOCs by a Broad Spectrum Antibody 8G3

H. Ma, C.-T. K. Tseng, H. Zong, Y. Liao, Y. Ke, H. Tang, L. Wang, Z. Wang, Y. He, Y. Chang, S. Wang, A. Drelich, J. Hsu, V. Tat, Y. Yuan, , J. Zhu

This study evaluates the neutralization efficacy of antibodies against SARS-CoV-2 Omicron and other variants, finding that antibody 8G3 maintains broad neutralizing activity while EUA antibodies lose effectiveness.

bioRxiv · Feb 25, 2022 · PreprintCell Biology

Comprehensive Evaluation of ACE2-Fc Combination with Neutralization Antibody on Broad Protection against SARS-CoV-2 and Its Variants

H. Tang, Y. Ke, H. Ma, L. Han, L. Wang, H. Zong, Y. Yuan, Z. Wang, Y. He, Y. Chang, S. Wang, J. Liu, Y. Yue, W. Xu, X. Zhang, , J. Zhu

This study evaluates ACE2-Fc combined with neutralizing antibodies against SARS-CoV-2 variants, showing enhanced neutralization and resistance to escape mutations.

bioRxiv · Jan 17, 2022 · PreprintCell Biology

Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

H. Ma, Y. Guo, H. Tang, C.-T. Tseng, L. Wang, H. Zong, Z. Wang, Y. He, Y. Chang, S. Wang, H. Huang, Y. Ke, Y. Yuan, M. Wu, Y. Zhang, , J. Zhu

This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.

bioRxiv · Sep 24, 2021Cell Biology

Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis

X. He, J. Liu, C. Liang, A. B. Shaikh, K. Zheng, L. Dang, B. Guo, D. Li, C. Lu, Q. Guo, D. Fan, Y. Bian, H. Feng, L. Xiao, X. Pan, , A. Lu

This study shows that PLEKHO1 in osteoblasts worsens joint inflammation in RA and promotes bone formation, suggesting it as a therapeutic target.

bioRxiv · Jul 30, 2018Cell Biology