Copper transport to mitochondria by SLC25A3 contributes to skeletal myoblast differentiation and is required for survival of differentiated myotubes
Alexandra M Perez, Jason D. Fivush, Bailey M Cordill, Nathan Ferguson, Y Zhang, Allison T. Mezzell, Ushodaya Mattam, Omar Chaudhry, Karleigh G Porter, Saanvi Maadaadi, Dina Secic, Megan E. Bischoff, Karthickeyan Chella Krishnan, Rhett A. Kovall, Tom Cunningham, , Katherine E. Vest
This study shows that SLC25A3-mediated copper transport to mitochondria is essential for skeletal myoblast differentiation and survival of mature myotubes.
bioRxiv · Jun 7, 2026 · PreprintCell Biology