Author

Dina Secic

University of CincinnatiORCID 0000-0002-0041-1294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

John T. CunninghamiD· 3 shared Katherine E. VestiD· 3 shared Maria Czyzyk-KrzeskaiD· 3 shared Megan E. BischoffiD· 3 shared Jarek MelleriD· 2 shared Juechen YangiD· 2 shared Julio Alberto Landero FigueroaiD· 2 shared L. Ph. H. SchmidtiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

John T. CunninghamORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 7, 2026

Copper transport to mitochondria by SLC25A3 contributes to skeletal myoblast differentiation and is required for survival of differentiated myotubes

Alexandra M Perez, Jason D. Fivush, Bailey M Cordill…·Katherine E. Vest

This study shows that SLC25A3-mediated copper transport to mitochondria is essential for skeletal myoblast differentiation and survival of mature myotubes.

DOI 10.64898/2026.06.03.729837

mouseexperimental assay

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BiochemistryJournal of Biological ChemistryPeer-reviewedFeb 12, 2026

Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS)

Dina Secic, Megan E. Bischoff, L. Ph. H. Schmidt…·Maria Czyzyk-Krzeska

This study uses SEC-ICP-MS to assess copper allocation to cytochrome c oxidase and identifies key transporters involved in mitochondrial copper trafficking.

1 citation

metabolomicsexperimental assay

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Cancer BiologyCancer DiscoveryPeer-reviewedOct 30, 2024

Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma

Megan E. Bischoff, Behrouz Shamsaei, Juechen Yang…·Maria Czyzyk-Krzeska

This study shows copper drives metabolic remodeling and progression in clear cell renal cell carcinoma by coordinating bioenergy, biosynthesis, and redox homeostasis.

32 citationstop 4%

humanbulk RNA-seq

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