Karthickeyan Chella Krishnan

Shared and Divergent Features of Cardiac Transcriptome and Glucose Metabolism Markers in Human and Mouse HFpEF

This study compares cardiac transcriptome and glucose metabolism markers in human and mouse HFpEF, finding greater conservation in right ventricles and sex-specific differences in left ventricles.

Copper transport to mitochondria by SLC25A3 contributes to skeletal myoblast differentiation and is required for survival of differentiated myotubes

This study shows that SLC25A3-mediated copper transport to mitochondria is essential for skeletal myoblast differentiation and survival of mature myotubes.

Isolated Mouse Adult Cardiomyocytes Display Minimal Mitochondrial ATP Demand and Maximal Reliance on Glycolysis

This study characterizes bioenergetic and glycolytic profiles in three cardiomyocyte models, revealing distinct metabolic adaptations in mouse adult cardiomyocytes.

Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy

The paper identifies three genetic loci influencing mitochondrial proteins and heart hypertrophy in mice using proteomics and association mapping.

Differential Metabolic and Multi-tissue Transcriptomic Responses to Fructose Consumption among Genetically Diverse Mice

This study examines how fructose affects metabolic and transcriptomic responses in genetically diverse mice, identifying strain-specific pathways and regulators involved in metabolic dysfunctions.