Katherine E. Vest

Copper transport to mitochondria by SLC25A3 contributes to skeletal myoblast differentiation and is required for survival of differentiated myotubes

This study shows that SLC25A3-mediated copper transport to mitochondria is essential for skeletal myoblast differentiation and survival of mature myotubes.

Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS)

This study uses SEC-ICP-MS to assess copper allocation to cytochrome c oxidase and identifies key transporters involved in mitochondrial copper trafficking.

The copper chaperone ATOX1 exhibits differential protein-protein interactions and contributes to skeletal myoblast differentiation

The paper investigates ATOX1's protein-protein interactions during myoblast differentiation and shows its dynamic interactome contributes to skeletal myoblast differentiation.

Oculopharyngeal muscular dystrophy (OPMD) associated alanine expansion impairs the function of the nuclear polyadenosine RNA binding protein PABPN1 as revealed by proximity labeling and comparative proteomics

This study shows that alanine expansion in PABPN1 impairs its function in skeletal muscle, leading to OPMD, through loss of function and dominant negative effects.