Selective targeting of a histone-like silencer Sfx to the R6K conjugal transfer operon
Bing Wang, Ritika Gupta, Nathan Blaine, Barbare Khitiri, Catherine Jordan, Natalia Molotievskiy, David D Dunlap, Laura Finzi, Irina Artsimovitch
The paper shows that Sfx, a histone-like protein in R6K plasmid, selectively silences the vir operon by forming stable nucleoprotein filaments and phase separating with plasmid DNA.
Nucleic Acids Research · May 29, 2026Peer-reviewedMolecular Biology