Laura Finzi

This study characterizes the physico-chemical properties of ParB-parS condensates and their mechanical response, suggesting a mechanism for bacterial chromosome segregation.

The paper shows that Sfx, a histone-like protein in R6K plasmid, selectively silences the vir operon by forming stable nucleoprotein filaments and phase separating with plasmid DNA.

This study shows that macromolecular crowding promotes DNA writhe under tension by inducing a contractile force dependent on crowder concentration and molecular weight.