Christophe Herman

This study identifies the role of the ω subunit in stabilizing RNA polymerase to balance processivity and collision resolution during transcription.

This study shows that low-dose cephaloridine induces colanic acid production in gut bacteria, extending host lifespan in C. elegans and mice.

This study shows that MuGam inhibits DNA break repair by slowing DNA resection and that GreA loss restores repair by releasing MuGam, linking transcription to DNA repair in E. coli.

The paper identifies specific bacterial metabolites affecting C. elegans physiology and develops an RNA interference strain to study genotype-phenotype interactions without microbial confounding.