Ritika Gupta

Biophysical Characterization of ParBS Condensates suggests a physical mechanism for segregation

This study characterizes the physico-chemical properties of ParB-parS condensates and their mechanical response, suggesting a mechanism for bacterial chromosome segregation.

Selective targeting of a histone-like silencer Sfx to the R6K conjugal transfer operon

The paper shows that Sfx, a histone-like protein in R6K plasmid, selectively silences the vir operon by forming stable nucleoprotein filaments and phase separating with plasmid DNA.

Histone H3 tail charge patterns govern nucleosome condensate formation and dynamics

This study shows how charge patterns in the H3 tail affect nucleosome condensate formation and dynamics through phase separation mechanisms.

Biomolecular Condensates Can Enhance Homotypic RNA Clustering

This study shows that repeat RNAs form nanoscale clusters within biomolecular condensates, driven by sequence features and RNA secondary structure, and that G3BP1 buffers these interactions.