Aging and viral evolution impair immunity against dominant pan-coronavirus-reactive T cell epitope
Lucie Loyal, Karsten Jürchott, Ulf Reimer, Lil Meyer‐Arndt, Larissa Henze, Norbert Mages, Jak Kostrzanowski, Bernhard Reus, Maike Mangold, Beate Kruse, Manuela Dingeldey, Birgit Sawitzki, Janine Michel, Marica Grossegesse, Karsten Schnatbaum, , Andreas Thiel
The paper investigates how aging and viral mutations affect pan-coronavirus immunity, finding reduced T cell responses in older individuals and mutation-driven impact on humoral immunity.
European Journal of Immunology · Jul 1, 2025Peer-reviewedImmunology