Author

Marica Grossegesse

Robert Koch InstituteORCID 0000-0002-9369-8203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Andreas NitscheiD· 2 shared Andreas ThieliD· 1 shared Beate Kruse· 1 shared Bernd Timmermann· 1 shared Bernhard ReusiD· 1 shared Birgit SawitzkiiD· 1 shared Christin Mache· 1 shared Claudia Giesecke‐ThieliD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Andreas NitscheORCID

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2 papers

Recent·Most cited

ImmunologyEuropean Journal of ImmunologyPeer-reviewedJul 1, 2025

Aging and viral evolution impair immunity against dominant pan-coronavirus-reactive T cell epitope

Lucie Loyal, Karsten Jürchott, Ulf Reimer…·Andreas Thiel

The paper investigates how aging and viral mutations affect pan-coronavirus immunity, finding reduced T cell responses in older individuals and mutation-driven impact on humoral immunity.

3 citations

humanproteomics

𝕏 PostBluesky

Systems BiologyJournal of Proteome ResearchPeer-reviewedJan 4, 2022

Deep time course proteomics of SARS-CoV and SARS-CoV-2-infected human lung epithelial cells (Calu-3) reveals strong induction of interferon-stimulated gene (ISG) expression by SARS-CoV-2 in contrast to SARS-CoV

Marica Grossegesse, Daniel R. Bourquain, Markus Neumann…·Joerg Doellinger

This study compares protein expression changes in SARS-CoV and SARS-CoV-2 infected Calu-3 cells, revealing stronger interferon-stimulated gene induction by SARS-CoV-2.

22 citations

humanproteomics

𝕏 PostBluesky