Orphan Non-Coding RNAs Drive Tumorigenesis and Enable Pre-Diagnostic Detection in HPV-Negative Head and Neck Cancer
Hoang C B Nguyen, Lishi Li, Benedict Choi, Mehran Karimzadeh, Jack Ghannam, Jeffrey Wang, Yana Al-Inaya, Gjystina Lumaj, Fereydoun Hormozdiari, Allen L. Feng, Jeremy D. Richmon, Daniel G. Deschler, Mark Alex Varvares, Daniel L. Faden, Derrick T. Lin, Hani Goodarzi
This study identifies oncRNAs as drivers of HPV-negative head and neck cancer and shows their potential for pre-diagnostic detection.
bioRxiv · Dec 25, 2025 · PreprintCancer Biology