Slit3 Fragments Orchestrate Neurovascular Expansion and Thermogenesis in Brown Adipose Tissue
Tamires Duarte Afonso Serdan, Heidi E. Cervantes, Benjamin Frank, Akhil Gargey, Qiyu Tian, Daniel Hope, Chan Hee J. Choi, Anne Hoffmann, Adhideb Ghosh, Christian Wolfrum, Matthew Blake Greenblatt, Paul Cohen, Matthias Blüher, Halil Aydin, Gary J. Schwartz, Farnaz Shamsi
This study identifies Slit3 fragments that coordinate neurovascular expansion and thermogenesis in brown adipose tissue by regulating angiogenesis and sympathetic innervation.
Nature Communications · Mar 25, 2026Peer-reviewedCell Biology