Kinetic logic of uridylation-mediated RNA decay
Annamaria Sgromo, Benjamin M. Jordan, Andrew Aarestad, David Mörsdorf, F. Boneberg, Martin Jínek, Thomas Rainer Burkard, Niko P. Popitsch, Stefan Ludwig Ameres
This study investigates how uridylation mediates RNA decay in Drosophila by showing how Tailor generates oligo(U) intermediates and how Dis3l2 decodes these to initiate decay.
bioRxiv · Mar 27, 2026 · PreprintBiochemistry