Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response
Mikhail Roshal, Isabella Y. Kong, Wikum Dinalankara, Jonathan B. Reichel, Matt R. Teater, Bhavneet Binder, Sakellarios Zairis, Joshua Brody, Sunita I. Park, Alexandra E. Kovach, Nitya Gulati, Matthew James Oberley, Megan S. Lim, Matthew John Barth, Olivier Elemento, , Ethel Cesarman
This study identifies unique transcriptional features of Hodgkin lymphoma HRS cells, including immune evasion mechanisms and an unfolded protein response, distinguishing them from other B-cell lymphomas.
Blood Cancer Journal · Apr 22, 2026Peer-reviewedCancer Biology