(R)-S-Adenosyl-L-methionine hydrolases counter sulfonium epimerisation in thermophilic archaea
A. Bartels, Michael K. F. Mohr, Phillip Nußbaum…·Jennifer N. Andexer
This study identifies SAM hydrolases in thermophilic archaea that counteract sulfonium epimerisation, maintaining metabolic stability by degrading inactive (RS,SC)-SAM.