De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy
Yuda Chen, Klaus Yserentant, Kibeom Hong, Y. P. Kuang, Arghya Bhowmick, Arthur Charles‐Orszag, Samuel J. Lord, Lei Lü, Kai-Peng Hou, Samuel I. Mann, Jonathan B. Grimm, Luke D. Lavis, R. Dyche Mullins, William F. DeGrado, Bo Huang
This paper designs de novo Rhodamine Binder (Rhobin) tags with high brightness, stability, and applicability in live-cell imaging and extreme conditions.
bioRxiv · Jun 24, 2025 · PreprintBioengineering