R. Dyche Mullins

This study identifies a geothermal amoeba that divides at 63°C, setting a new upper temperature limit for eukaryotes and challenging existing paradigms about eukaryotic thermal tolerance.

The paper uses theory and simulation to show that membrane surfaces can accelerate actin filament assembly by clustering polymerases, even at high actin concentrations.

This study identifies layilin as a regulator of Treg motility and suppressive capacity in skin, showing its role in adhesion and inflammation.

This paper designs de novo Rhodamine Binder (Rhobin) tags with high brightness, stability, and applicability in live-cell imaging and extreme conditions.

This study investigates how SegA and SegB proteins in Sulfolobus acidocaldarius work together to segregate chromosomes, revealing a bipolar structure distinct from bacterial systems.

The paper shows that most actin subunits in lamellipodial networks come from membrane-associated polymerases, not directly from solution.

This study shows that neuronal DNA double-strand breaks, even when accumulated due to loss of C-NHEJ, do not drive brain aging or neurodegeneration in mice.

The paper derives expressions for critical concentrations of dynamically unstable polymers, showing how nucleotide hydrolysis and spontaneous nucleation rates affect their assembly.

The paper shows apoE4 increases VASP phosphorylation, disrupting actin interactions and affecting neurite outgrowth in Neuro-2a cells.