CellSIUS provides sensitive and specific detection of rare cell populations from complex single cell RNA-seq data
Rebekka Wegmann, Marilisa Neri, Sven Schuierer, Bilada Bilican, Huyen Hartkopf, Florian Nigsch, Felipa Mapa, Annick Waldt, Rachel Cuttat, Max R. Salick, Joe Raymond, Ajamete Kaykas, Guglielmo Roma, Caroline Gubser Keller
The paper benchmarks scRNA-seq methods and introduces CellSIUS, a tool that improves detection of rare cell populations and identifies their functional signatures in human stem cell differentiation.
Genome biology · Jul 17, 2019Peer-reviewedBioinformatics