Rebekka Wegmann

The paper identifies an RFX-driven ciliogenic cell state in colorectal cancer that is sensitive to FGFR inhibitors and associated with poor prognosis.

This paper introduces scClone2DR, a framework predicting tumour drug response at the clone level using single-cell DNA/RNA sequencing and drug-screening data, showing improved accuracy in identifying clonal sensitivities and resistance.

The paper profiles the metabolome of 180 cancer cell lines and identifies two major metabolic types linked to epithelial-mesenchymal transition (EMT).

The paper benchmarks scRNA-seq methods and introduces CellSIUS, a tool that improves detection of rare cell populations and identifies their functional signatures in human stem cell differentiation.