Integrated Genomic Analyses Identify High-Risk Factors and Actionable Targets in T-Cell Acute Lymphoblastic Leukemia
Haichuan Zhu, Bingjie Dong, Yingchi Zhang, Mei Wang, Jianan Rao, Bowen Cui, Yu Liu, Qian Jiang, Weitao Wang, Lu Yang, Anqi Yu, Zongru Li, Chao Liu, Le‐Ping Zhang, Xiao‐Jun Huang, , Hong Wu
The paper identifies high-risk factors and actionable targets in T-ALL through integrated genomic and transcriptomic analyses of 165 patients, finding RAS pathway and PTEN mutations as poor survival factors and potential therapeutic targets.
Blood Science · Jan 1, 2022Peer-reviewedGenetic & Genomic Medicine