Lu Yang

This paper introduces time-resolved fluorescent proteins (TRFPs) that enable temporal-spectral resolved microscopy for multiplexed imaging and super-resolution in live cells.

This study identifies calcineurin as a phosphatase that dephosphorylates SIK3 at specific sites, linking it to sleep regulation in mice.

The paper identifies high-risk factors and actionable targets in T-ALL through integrated genomic and transcriptomic analyses of 165 patients, finding RAS pathway and PTEN mutations as poor survival factors and potential therapeutic targets.

The paper identifies 3D genome alterations and enhancer hijacking mechanisms in T-lineage acute lymphoblastic leukemia (T-ALL) using integrated analyses of 18 patients and 4 controls.