Author

Le‐Ping Zhang

Peking University People's HospitalORCID 0000-0002-5233-8738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Bingjie Dong· 2 shared Haichuan ZhuiD· 2 shared Hong WuiD· 2 shared Lu YangiD· 2 shared Qian JiangiD· 2 shared Weitao WangiD· 2 shared Xiao‐Jun HuangiD· 2 shared Anqi YuiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Bingjie Dong

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2 papers

Recent·Most cited

Integrated Genomic Analyses Identify High-Risk Factors and Actionable Targets in T-Cell Acute Lymphoblastic Leukemia

Haichuan Zhu, Bingjie Dong, Yingchi Zhang, Mei Wang, Jianan Rao, Bowen Cui, Yu Liu, Qian Jiang, Weitao Wang, Lu Yang, Anqi Yu, Zongru Li, Chao Liu, Le‐Ping Zhang, Xiao‐Jun Huang, , Hong Wu

The paper identifies high-risk factors and actionable targets in T-ALL through integrated genomic and transcriptomic analyses of 165 patients, finding RAS pathway and PTEN mutations as poor survival factors and potential therapeutic targets.

Blood Science · Jan 1, 2022Peer-reviewedGenetic & Genomic Medicine

3D Genome Analysis Identifies Enhancer Hijacking Mechanism for High-Risk Factors in Human T-Lineage Acute Lymphoblastic Leukemia

Lu Yang, Fengling Chen, Haichuan Zhu, Yang Chen, Bingjie Dong, Minglei Shi, Weitao Wang, Qian Jiang, Le‐Ping Zhang, Xiao‐Jun Huang, Michael Q. Zhang, Hong Wu

The paper identifies 3D genome alterations and enhancer hijacking mechanisms in T-lineage acute lymphoblastic leukemia (T-ALL) using integrated analyses of 18 patients and 4 controls.

bioRxiv · Mar 11, 2020 · PreprintGenomics