Author

Binzhi Qian

Shanghai Medical College of Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 4 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:spatial transcriptomics· 4 Organism:mouse· 3 Research Focus:database / resource· 2 Research Focus:dimensionality reduction· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1

Frequent Co-Authors

Zhiyuan YuaniD· 3 shared Daoliang ZhangiD· 2 shared Qi ZouiD· 2 shared Adriano G Rossi· 1 shared Alexander Adima· 1 shared Amil Mair· 1 shared Bingjie DaiiD· 1 shared Calum T Robb· 1 shared

Activity by Year

2020-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioinformatics

Zhiyuan YuanORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Histology-aware Inference of Cell-cell Communication in Spatial Transcriptomics

Xiaofei Wang, Chenyang Tao, Yu Jiang, Yixuan Jiang, Hanyu Liu, Zheng Jiang, Pinan Zhu, Ningfeng Que, Jianzhong Xi, Stephen Price, Binzhi Qian, Jianguo Xu, Chao Li

This paper introduces HARMONIC, a framework that improves cell-cell communication inference in spatial transcriptomics by incorporating histology data, showing it better captures anatomical context.

bioRxiv · Oct 12, 2026 · PreprintBioinformatics

Deciphering the gene-centric spatial dynamics across tissue and time with GeneSPOT

Qi Zou, Zhikang Wang, Sijie Li, Senlin Lin, Chuangyi Han, Yan Cui, Shengxi Li, Lin Wang, Daoliang Zhang, Wei Zhang, Binzhi Qian, Rui Gao, Zhiyuan Yuan

GeneSPOT is a gene-centric framework that characterizes spatial gene relationships and their reorganization across biological conditions and time.

bioRxiv · Sep 29, 2026 · PreprintBioinformatics

Robust integration of weakly anchored spatial multi-omics

Chuyao Wang, Yonghao Liu, Zi Wang, Pinli Sun, Zhi Li, Li J, Xueting Wang, K C Chen, Qi Zou, Daoliang Zhang, Zheqi Hu, Yixuan Du, Binzhi Qian, Xiaoyue Feng, Zhiyuan Yuan, Renchu Guan

This paper introduces SpaWeaver, a framework for robust spatial multi-omics integration using weak anchors, showing improved performance in handling real-world challenges and enabling new biological insights.

bioRxiv · Jun 16, 2026 · PreprintBioinformatics

A lightweight, ultrafast and general embedding framework for large-scale spatial omics data

Bingjie Dai, Yuchao Liang, Litai Yi, Pengwei Hu, Yancheng Song, Binzhi Qian, Miaoxia He, Linhui Wang, Zhiyuan Yuan, Yongchun Zuo

This paper introduces SpaLP, a framework for spatial omics data that outperforms existing methods in efficiency and accuracy across multiple tasks.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics

Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells

Siobhan Crittenden, Marie Goepp, Jolinda Pollock, Calum T Robb, Danielle J Smyth, You Zhou, Robert Andrews, Victoria Tyrrell, Alexander Adima, Richard A OConnor, Luke Davies, Xue-Feng Li, Hatti X Yao, Gwo-Tzer Ho, Xiaozhong Zheng, , Chengcan Yao

This study shows that prostaglandin E2 inhibits microbiota-dependent regulatory T cells, leading to increased intestinal inflammation.

bioRxiv · Jul 12, 2020Immunology