Menin regulates oncogenic cell identity transcriptional networks in multiple myeloma
Emily Gruber, Subhasree Kumar, Rheana L. Franich, Tiffany T. Khong, Daniel Neville, Ching‐Seng Ang, James The, Bradon Rumler, Shania Alex, Grace Dobbs, Alexander Charles Lewis, George Howitt, Edwin D. Hawkins, Peter Leif Bergsagel, Marta Chesi, , Lev M. Kats
This study identifies Menin as a key regulator of oncogenic gene expression in multiple myeloma and shows that Menin inhibitors are effective in myeloma cell lines and models.
bioRxiv · Jun 19, 2026 · PreprintCancer Biology