Naegleria fowleri: protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein, Jared W. Lassner, Bram Osterhout, Nathan L. Tran, Lily Xu, Ryan M. Young, Justin K. Craig, Ian K. H. Chun, David M. Dranow, Jan A. Abendroth, Silvia L. Delker, Douglas R Davies, Stephen J. Mayclin, , Wesley C. Van Voorhis A
The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.
PLoS ONE · Mar 24, 2021Peer-reviewedMolecular Biology