Author

Jan A. Abendroth

UCB Pharma (United States)ORCID 0000-0002-8229-3243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Bart L. StakeriD· 2 shared Peter John MyleriD· 2 shared Sandhya SubramanianiD· 2 shared Bram Osterhout· 1 shared Brandy M. CalhouniD· 1 shared Chelsea Agyei· 1 shared Christopher A. RiceiD· 1 shared Craig L. SmithiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Bart L. StakerORCID

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Author profile →

2 papers

Recent·Most cited

Structural Basis of Glycolytic Control in Trypanosoma cruzi: Insights from Enolase and PGI

Kenneth Austin, Vincent A Obakachi, Florence Lisa Muzenda, Marakiya T. Moetlediwa, Chelsea Agyei, Timothy Craig, Jan A. Abendroth, Mary Nguyen, Ngoc Tran, Bart L. Staker, Tom Edwards, Sandhya Subramanian, Peter John Myler, Tawanda Zininga, Krishna Kuben Govender, Graham Chakafana

The paper reports high-resolution structures of T. cruzi glycolytic enzymes and identifies potential inhibitors through structural analysis and virtual screening.

bioRxiv · Jan 15, 2026 · PreprintBiochemistry

Naegleria fowleri: protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein, Jared W. Lassner, Bram Osterhout, Nathan L. Tran, Lily Xu, Ryan M. Young, Justin K. Craig, Ian K. H. Chun, David M. Dranow, Jan A. Abendroth, Silvia L. Delker, Douglas R Davies, Stephen J. Mayclin, , Wesley C. Van Voorhis A

The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.

PLoS ONE · Mar 24, 2021Peer-reviewedMolecular Biology