High-performance genetically-encoded green and red fluorescent biosensors for pyruvate
Shosei Imai, Saaya Hario, Carl Suerte, Issei Yamaguchi, Kenryo Sakoi, Adam Thuen, Brekken Meznarich, Mikhail A. Drobizhev, Takuya Terai, Kei Takahashi, Robert E. Campbell
The paper develops high-performance green and red fluorescent biosensors for pyruvate with large fluorescence intensity changes and varying affinities, enabling multicolor imaging in mammalian cells.
bioRxiv · Apr 17, 2025 · PreprintMolecular Biology