Author
Japan Science and Technology AgencyORCID 0000-0002-3425-3589Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Ikumi Miyazaki, Kelvin Tsao, Takuya Terai, Kei Takahashi, Robert E. Campbell
The paper develops a new calcium indicator, HiCaRI, based on the photostable mStayGold protein, showing improved brightness and photostability compared to existing GFP-based indicators.
bioRxiv · Oct 12, 2026 · PreprintBioengineering
Toru Komatsu, Shosei Imai, Masaki Tajima, Yuki Sugiura, Takumi Iwasaka, Mayano Minoda, Yu Kagami, Kazufumi Honda, Takuya Terai, Reiko Tsuchiya, Ryosuke Kojima, Yasuteru Urano, Hiroyuki Kusuhara, Tadahaya Mizuno, Robert E. Campbell
This paper introduces a biosensor-based method for single-molecule enzyme activity profiling without enzyme-specific substrates, enabling absolute quantification of active enzyme molecules in cellular and circulating samples.
bioRxiv · Sep 22, 2026 · PreprintBiochemistry
Michael Chang, Lilly Nash, Ruben Bierings, Kei Takahashi, Takuya Terai, Tom D. Carter, Robert E. Campbell, Kelvin Tsao
The paper develops a photostable pH biosensor called serapH using mStayGold as a scaffold and introduces a screening method for pH-sensitive FPs in bacterial colonies.
ChemBioChem · Aug 26, 2026Peer-reviewedBiochemistry
Abhi Aggarwal, Heather A. Baker, Céline D. Dürst, I-Wen Chen, Pablo de Chambrier, Carrie Stine, Julia Marie Gonzales, Jonathan S. Marvin, Milène Vandal, Torgny Lundberg, Cherie A. Brown-Panton, Kenryo Sakoi, Ronak H. Patel, Chenger Wang, Frank Visser, , Alexander W. Lohman
The paper introduces OCaMP, an orange fluorescent calcium indicator that improves sensitivity and performance compared to existing green and red indicators for neural imaging.
Nature Communications · Jun 22, 2026Peer-reviewedNeuroscience
Ryan Fink, Shosei Imai, Nala Gockel, German Lauer, Kim Renken, Jonas Wietek, Paul J. Lamothe‐Molina, Falko Fuhrmann, Manuel Mittag, Tim Ziebarth, Annika Canziani, Martin Kubitschke, Vivien Kistmacher, Anny Kretschmer, Eva Sebastian, , Olivia Andrea Masseck
The paper introduces PinkyCaMP, a new red fluorescent calcium sensor with improved brightness, photostability, and compatibility with optogenetics and neurotransmitter imaging.
Nature Methods · Apr 24, 2026Peer-reviewedNeuroscience
Shosei Imai, Saaya Hario, Carl Suerte, Issei Yamaguchi, Kenryo Sakoi, Adam Thuen, Brekken Meznarich, Mikhail A. Drobizhev, Takuya Terai, Kei Takahashi, Robert E. Campbell
The paper develops high-performance green and red fluorescent biosensors for pyruvate with large fluorescence intensity changes and varying affinities, enabling multicolor imaging in mammalian cells.
bioRxiv · Apr 17, 2025 · PreprintMolecular Biology
Rochelin Dalangin, Bill Jia, Yitong Qi, Abhi Aggarwal, Kenryo Sakoi, Mikhail A. Drobizhev, Rosana S. Molina, Ronak H. Patel, Ahmed S. Abdelfattah, Jihong Zheng, Daniel Reep, Jeremy P. Hasseman, The GENIE Project Team, Getahun Tsegaye, Arthur Tsang, , Robert E. Campbell
This paper introduces two new far-red fluorescent GECIs, FR-GECO1a and FR-GECO1c, characterized for their Ca2+ sensitivity and performance in neuronal imaging.
Nature Communications · Apr 7, 2025Peer-reviewedNeuroscience